Drug Discovery and Development Programs

Broad-Spectrum Ebola Program

• Oral small molecule antiviral
• Active against multiple ebolavirus species
• Post-infection efficacy demonstrated in animal models
• Government-supported development pathway
• Intended for outbreak preparedness and biodefense applications
• Seeking strategic investor and co-development opportunities

Lassa Fever Program

• Phase 2 Clinical-stage antiviral
• Human safety and PK established
• Supported through U.S. government funding
• Developed for the prevention and treatment of Lassa fever

Metabolic Disease Program

• Preclinical reductions in body weight, triglycerides and adipose tissue
• Preservation of muscle mass in animal models
• Initial translational human clinical triglyceride reduction and hepatocyte metabolism
• Evaluation ongoing across cardiometabolic indications
• Seeking strategic co-development and investor partnerships